The Canadian Regenerative Medicine Center

The Canadian regenerative Medicine Center for Diabetes Complications is a health care business cooperation model between  two Canadian medical companies DCare Medical Canada , the leader in regenerative medicine  therapy  , Technology  transfer  and  research support   and  Xediton Pharmaceuticals Inc . a privately-held pharmaceutical company focus on meeting the needs of patients, physicians and partners for the regenerative medicine devices and materials .

We understand the diabetes complications medical dilemma , we believe that every second around 40 Limbs are amputees world wide due to diabetic foot , Millions of patients now suffer with chronic wounds that impact, impair or cause loss of life because of issues associated with diabetes , infection and immunity, vascular insufficiency,  or excessive pressure.

The current evidence-based and palliative treatments are increasingly unable to keep pace with patients’ needs, especially given our aging population. There are few effective ways to treat the root causes of many Chronic wounds In many cases, clinicians can only manage patients’ symptoms using medications or devices.

Now Regenerative medicine is a game-changing area of medicine with the potential to fully heal damaged tissues and organs, offering solutions and hope for people who have conditions that today are beyond repair.

It is widely recognized that cell-based therapies could revolutionize health care for a range of diabetes complications , and that there are gaps in the overarching framework and technologies to generate clinical success. There is limited understanding of how to fulfill requirements as regulatory and manufacturing guidelines are incomplete and few have achieved commercialization. Recent developments are encouraging adoption of automation and quality engineering approaches for bioprocessing of cell-based therapies. Include technology development to improve the cost and purity of manufacture and final product quality.

 Training of the professionals on how to manipulate the processing of manufacturing and application of the end product   play an important part of the  treatment  success.

REG Center Brochure

Guidelines introduction

Protocols

Therapeutic Protocols :

1- Chronic Wound Protocols :  {Cytowound™ }

The latest  regenerative medicine Therapeutic protocol  for all Chronic wounds may affect Diabetic patients

{ Please ask about the full scientific book for Cytowound™ }

2- Skin disorders { Cytoderm™ }

We provide a regenerative medicine solution for all skin complications may affect diabetic patients .

{ Please ask about the full scientific book for Cytoderm™ }

3- Orthopedic Complications { Cytofix™ }

we provide a regenerative medicine solution for Chracot’s Joint , delayed union and non union fracture , bone trauma

{ Please ask about the full scientific book for CytoFix™ } 

4- Plastic surgery { Cytograft™ }

a regenerative medicine reconstruction technique

{ Please ask about the full scientific book for Cytograft™ }

The Project is launched Now in The Gulf  and Middle East Countries

Diabetes and Immune dysfunction

Patients with diabetes mellitus (DM) have infections more often than those without DM. The course of the infections is also more complicated in this patient group. One of the possible causes of this increased prevalence of infections is defects in immunity. Besides some decreased cellular responses in vitro, no disturbances in adaptive immunity in diabetic patients have been described. Different disturbances (low complement factor 4, decreased cytokine response after stimulation) in humoral innate immunity have been described in diabetic patients. However, the clinical relevance of these findings is not clear. Concerning cellular innate immunity most studies show decreased functions (chemotaxis, phagocytosis, killing) of diabetic polymorphonuclear cells and diabetic monocytes/macrophages compared to cells of controls. In general, a better regulation of the DM leads to an improvement of these cellular functions. Furthermore, some microorganisms become more virulent in a high glucose environment. Another mechanism which can lead to the increased prevalence of infections in diabetic patients is an increased adherence of microorganisms to diabetic compared to nondiabetic cells. This has been described for Candida albicans. Possibly the carbohydrate composition of the receptor plays a role in this phenomenon.