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Chitosan-based nanomaterials have made great help for the creation of new, appropriate materials for use in a there are numerous application in biomedicine, like tissue engineering, and skin regeneration , Nanoparticles (NPs), nanogels, and nanofibrous scaffolds are the most prevalent types of chitosan-based nanomaterials. Nanomaterials have significant benefits related to their nanometer sizes, such as their very large surface area compared with their volume and the capacity to enter into cytoplasmic space (increased cellular uptake).
Chitosan-based NPs have furthermore been used for wound healing to chitosan-based nanofibrous scaffolds for the continuous release of therapeutic agents (such as growth factors or antibiotics) in skin tissue regeneration .
REGEDERM ” Chitosan Complex Natural Plant Base Formula ” play roles mainly in the first three stages during wound healing. Firstly, they help stop hemorrhaging by promoting the aggregation of platelets and erythrocytes and inhibiting the dissolution of fibrin in the hemostasis stage; Secondly, they can assist to clear bacteria from the wound during the inflammation stage; Finally, they accelerate skin proliferation via promoting the growth of granulation tissue, which is called proliferation stage. After then, the wound was healed and the skin was remodeled to finish the healing route.
